Matrix metalloproteinases and tissue inhibitors of metalloproteinases in gingival crevicular fluid during orthodontic tooth movement

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Matrix metalloproteinases and tissue inhibitors of metalloproteinases in gingival crevicular fluid during orthodontic tooth movement.

Orthodontic tooth movement requires extensive re-modelling of the periodontium. Matrix metalloproteinases (MMPs) degrade the extracellular matrix during re-modelling, while their activity is regulated by the tissue inhibitors of metalloproteinases (TIMPs). The aim of this study was to investigate differences in MMP and TIMP levels in the gingival crevicular fluid (GCF) at the resorption and app...

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Matrix metalloproteinases -1, -2, -3, -7, -8, -12, and -13 in gingival crevicular fluid during orthodontic tooth movement: a longitudinal randomized split-mouth study.

This randomized split-mouth study aimed to examine the levels of matrix metalloproteinases (MMPs) -1, -2, -3, -7, -8, -12, and -13 in the gingival crevicular fluid (GCF) at different time points during orthodontic tooth movement. A total of 16 healthy orthodontic subjects (7 females, 9 males; mean age, 17.7 years) who needed their first upper premolars extracted were enrolled. One randomly chos...

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Identification of dentine sialoprotein in gingival crevicular fluid during physiological root resorption and orthodontic tooth movement.

Root resorption is an unwanted effect of orthodontic tooth movement. Analysis of dentine proteins in gingival crevicular fluid (GCF) is a potentially safer method of quantifying root resorption compared with conventional radiographic methods. This study aimed to identify and quantify the dentine-specific matrix protein, dentine sialoprotein (DSP), released into GCF during physiological root res...

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Biochemical markers of bone metabolism in gingival crevicular fluid during early orthodontic tooth movement.

OBJECTIVE To evaluate the expression of an activator of nuclear factor-kappa (RANK), osteoprotegerin (OPG), osteopontin (OPN), and transforming growth factor ß1 (TGF-ß1) in gingival crevicular fluid (GCF) of teeth subjected to orthodontic forces. MATERIALS AND METHODS A randomized, pilot clinical trial including 10 healthy volunteers was conducted using a split-mouth design. Orthodontic elast...

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Juveniles versus adults: differences in PGE2 levels in the gingival crevicular fluid during orthodontic tooth movement.

This study aimed to investigate age-related changes in the biosynthetic capacity of prostaglandin E2 (PGE2) in the gingival crevicular fluid (GCF) during one month of orthodontic treatment. Twenty-five juvenile subjects (mean age 13 +/- 2.1 years) and 23 adults (mean age 24 +/- 2.1 years) were included. GCF was collected immediately before the force application at the baseline, 2, 21 and 28 day...

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ژورنال

عنوان ژورنال: The European Journal of Orthodontics

سال: 2009

ISSN: 0141-5387,1460-2210

DOI: 10.1093/ejo/cjn127